Serum neuron-specific enolase (S-NSE) and the prognosis in small-cell lung cancer (SCLC): a combined multivariable analysis on data from nine centres

@article{Jrgensen1996SerumNE,
  title={Serum neuron-specific enolase (S-NSE) and the prognosis in small-cell lung cancer (SCLC): a combined multivariable analysis on data from nine centres},
  author={Lone G M J\orgensen and Kell Osterlind and Jos{\'e} Genoll{\'a} and Stephanie Gomm and Juan Ram{\'o}n Hern{\'a}ndez and Peter W M Johnson and J. L\ober and Ted A. W. Splinter and Monika Szturmowicz},
  journal={British Journal of Cancer},
  year={1996},
  volume={74},
  pages={463 - 467}
}
The influence of pretreatment serum neuron-specific enolase (S-NSE) in addition to more conventional prognostic factors on survival duration in small-cell lung cancer (SCLC) was investigated in 770 patients from nine centres in six countries. The other variables included stage of disease, performance status (PS), age, sex, serum lactate dehydrogenase (S-LDH), serum alkaline phosphatase (S-AP), and serum carcinoembryonic antigen (S-CEA). Increased values of S-NSE (> 12.5 micrograms-1 l) were… CONTINUE READING