Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study.

@article{Meuwese2007SerumML,
  title={Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study.},
  author={Marijn C. Meuwese and Erik S. G. Stroes and Stanley L. Hazen and Joram N. I. van Miert and Jan A. Kuivenhoven and Robert G. Schaub and Nicholas J Wareham and Robert L Luben and John J. P. Kastelein and Kay-tee Khaw and S. Matthijs Boekholdt},
  journal={Journal of the American College of Cardiology},
  year={2007},
  volume={50 2},
  pages={159-65}
}
OBJECTIVES We evaluated whether serum myeloperoxidase (MPO) levels are associated with the risk of future development of coronary artery disease (CAD) in apparently healthy individuals. BACKGROUND An enzyme of the innate immune system, MPO exhibits a wide array of proatherogenic effects. These include induction of oxidative damage to low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol and promotion of plaque vulnerability. Recent studies revealed that MPO… CONTINUE READING