Serum microRNAs in male subfertility—biomarkers and a potential pathogenetic link to metabolic syndrome

  title={Serum microRNAs in male subfertility—biomarkers and a potential pathogenetic link to metabolic syndrome},
  author={D. Trzybulska and J. Bobjer and A. Giwercman and C. Tsatsanis},
  journal={Journal of Assisted Reproduction and Genetics},
  pages={1277 - 1282}
PurposeThe purpose of the study was to identify serum microRNAs providing a link between male subfertility and metabolic syndrome (MetS) and validate their diagnostic potential.MethodsSera were analyzed for fertility and MetS-related parameters in subfertile men (n = 79) and controls (n = 38). Literature review identified miR-155-5p, miR-122-5p, miR-200a-3p, and miR-200c-3p which previously were associated with parameters of fertility as well as metabolic disorders. They were measured in the… Expand
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