Serum microRNA expression as an early marker for breast cancer risk in prospectively collected samples from the Sister Study cohort

Abstract

MicroRNAs (miRNAs) are small, non-coding, single-stranded RNAs between 18-22 nucleotides long that regulate gene expression. Expression of miRNAs is altered in tumor compared to normal tissue; there is some evidence that these changes may be reflected in the serum of cancer cases compared to healthy individuals. This has yet to be examined in a prospective… (More)
DOI: 10.1186/bcr3428

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