Serum miRNAs Expression and SNAP-25 Genotype in Alzheimer’s Disease

  title={Serum miRNAs Expression and SNAP-25 Genotype in Alzheimer’s Disease},
  author={S. Agostini and R. Mancuso and Gaia Liuzzo and E. Bolognesi and A. Costa and A. Bianchi and M. Clerici},
  journal={Frontiers in Aging Neuroscience},
MicroRNAs (miRNAs) are small non-coding RNAs that control gene expression by binding their 3′ untranslated region (3′UTR) region; these molecules play a fundamental role in several pathologies, including Alzheimer’s disease (AD). Synaptosomal-associated protein of 25 kDa (SNAP-25) is a vesicular protein of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) involved in neural plasticity and in the exocytosis of neurotransmitters, processes that are altered in AD… Expand
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