Serum miR-21 expression in human esophageal squamous cell carcinomas.

  title={Serum miR-21 expression in human esophageal squamous cell carcinomas.},
  author={E Cai and Yong-xin Gao and Zhong-zhi Wei and Wei-ying Chen and Ping Yu and Ke Li},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  volume={13 4},
To investigate the relationship between serum miRNA-21 (miR-21) expression in esophageal squamous cell carcinomas (ESCCs) and their clinicopathologic features, a 1:1 matched case-control study including 21 patients with ESCC and 21 age- and gender-matched healthy controls was carried out. Serum specimens were taken from all subjects. Total RNA was extracted and the stem-loop real time polymerase chain reaction was used to measure serum miR-21 in both groups. Clinical parameters were assessed to… CONTINUE READING