Serum mannose-binding lectin deficiency is associated with cryptosporidiosis in young Haitian children.

@article{Kirkpatrick2006SerumML,
  title={Serum mannose-binding lectin deficiency is associated with cryptosporidiosis in young Haitian children.},
  author={Beth D. Kirkpatrick and Christopher D. Huston and Dirk Wagner and Francine Noel and Pierre A Rouzier and Jean William Pape and Grylande Bois and Catherine J. Larsson and Wallace Kemper Alston and Katherine M Tenney and Cheryl Powden and James Paul O'Neill and Cynthia L Sears},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2006},
  volume={43 3},
  pages={289-94}
}
BACKGROUND Mannose-binding lectin (MBL) is a component of the innate immune response and binds microbial surfaces through carbohydrate recognition domains. MBL deficiency may contribute to susceptibility to a variety of infectious diseases, particularly in young children. MBL binds to the Cryptosporidium sporozoite and may be important in resistance to cryptosporidiosis. METHODS We studied the association of serum MBL levels and cryptosporidiosis in a case-control study of young Haitian… CONTINUE READING
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