Serum luteinizing hormone rises within minutes after depot leuprolide injection: implications for monitoring therapy.

@article{Bhatia2002SerumLH,
  title={Serum luteinizing hormone rises within minutes after depot leuprolide injection: implications for monitoring therapy.},
  author={Suruchi Bhatia and Elizabeth Neely and Darrell M. Wilson},
  journal={Pediatrics},
  year={2002},
  volume={109 2},
  pages={E30}
}
OBJECTIVE To find the time of the serum gonadotropin peak after depot leuprolide injection in children and to show that depot leuprolide therapy can be monitored by measuring serum luteinizing hormone (LH) immediately after injections. STUDY DESIGN We measured concentrations of leuprolide, LH, and follicle-stimulating hormone (FSH) at multiple time points before and after the first dose of depot leuprolide in 14 pubertal children beginning therapy. Gonadotropins and sex steroids were measured… CONTINUE READING

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