Serum levels of tumor necrosis factor-alpha, interleukin-1, and interleukin-6 in hemorrhagic fever with renal syndrome.

@article{Krakauer1995SerumLO,
  title={Serum levels of tumor necrosis factor-alpha, interleukin-1, and interleukin-6 in hemorrhagic fever with renal syndrome.},
  author={Teresa Krakauer and James W Leduc and Henry Krakauer},
  journal={Viral immunology},
  year={1995},
  volume={8 2},
  pages={75-9}
}
Hemorrhagic fever with renal syndrome is an acute viral disease caused by hantavirus. On the basis of clinical observation, the illness is divided into five sequential stages: febrile, hypotensive, oliguric, diuretic, and convalescent. Because interleukin-1 (IL-1), tumor necrosis factor-alpha (TNF-alpha), and interleukin-6 (IL-6) are mediators responsible for fever, septic shock, and acute phase protein induction, we examined, using ELISA, the presence of these three cytokines in 276 sera… CONTINUE READING

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