Serum levels of the pyridinoline crosslinked carboxyterminal telopeptide of type I collagen (ICTP) and osteocalcin in rachitic children in Nigeria.

@article{Scariano1995SerumLO,
  title={Serum levels of the pyridinoline crosslinked carboxyterminal telopeptide of type I collagen (ICTP) and osteocalcin in rachitic children in Nigeria.},
  author={John K Scariano and E A Walter and Robert Hayes Glew and Bruce W. Hollis and Andrew Henry and I Ocheke and Christian Ogoegbunem Isichei},
  journal={Clinical biochemistry},
  year={1995},
  volume={28 5},
  pages={541-5}
}
OBJECTIVES We measured the levels of the pyridinoline crosslinked carboxyterminal telopeptide of type I collagen (ICTP) and osteocalcin (OC) in the serum of 12 rachitic and 27 healthy Nigerian children, and compared the performance of these relatively new markers of bone metabolism with established laboratory parameters of skeletal disease. DESIGN AND METHODS Active rickets was diagnosed on the basis of clinical and biochemical criteria. Serum calcium and phosphorus concentration and alkaline… CONTINUE READING