Serum levels of the angiogenic factor pleiotrophin in relation to disease stage in lung cancer patients


Pleiotrophin is a heparin-binding growth factor involved in the differentiation and proliferation of neuronal tissue during embryogenesis, and also secreted by melanoma and breast carcinoma cells. Pleiotrophin exhibits mitogenic and angiogenic properties and has been shown to influence the vascular supply, expansion and metastasis of tumour cells. Our aim… (More)
DOI: 10.1038/sj.bjc.6600202

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