Serum levels of pregnenolone and 17-hydroxypregnenolone in patients with rheumatoid arthritis and systemic lupus erythematosus: relation to other adrenal hormones.

@article{Vogl2003SerumLO,
  title={Serum levels of pregnenolone and 17-hydroxypregnenolone in patients with rheumatoid arthritis and systemic lupus erythematosus: relation to other adrenal hormones.},
  author={Daniela Vogl and Werner Falk and Monika Dorner and Juergen Schoelmerich and Rainer H. Straub},
  journal={The Journal of rheumatology},
  year={2003},
  volume={30 2},
  pages={
          269-75
        }
}
OBJECTIVE In patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), low levels of adrenal steroids have been repeatedly demonstrated, but the site of alteration has not been exactly described because measurements of serum pregnenolone and 17-hydroxypregnenolone (17OHPreg) together with other adrenal steroids have never been performed. METHODS We measured serum levels of adrenal hormones such as pregnenolone, 17OHPreg, dehydroepiandrosterone (DHEA), DHEA sulfate (DHEAS… CONTINUE READING

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