Serum levels of neuron-specific enolase and s-100 protein after single tonic-clonic seizures

@article{Bttner1999SerumLO,
  title={Serum levels of neuron-specific enolase and s-100 protein after single tonic-clonic seizures},
  author={T. B{\"u}ttner and B. Lack and M. J{\"a}ger and Wolfgang W{\"u}nsche and W. Kuhn and T. M{\"u}ller and H. Przuntek and T. Postert},
  journal={Journal of Neurology},
  year={1999},
  volume={246},
  pages={459-461}
}
Abstract Serum neuron-specific enolase (s-NSE) and s-100 protein (s-100) are sensitive markers of various brain diseases. We investigated both of these markers in nine patients within 5 min, 6 h, 12 h, and 48 h after a single tonic-clonic seizure. The mean peak s-NSE level was significantly higher after 5 min (11.97 ± 8.56 μg/l) and 48 h (10.31 ± 8.92 μg/l, P < 0.05) than the levels of seizure-free, age-matched controls. Five patients had increased s-NSE levels regarding the upper limit of… Expand

Paper Mentions

Interventional Clinical Trial
The present study has been planned to assess the level of serum neuron-specific enolase (NSE) in focal seizures and its changes after antiepileptic therapy.  
ConditionsSeizures, Focal
InterventionDrug
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S100B and NSE serum concentrations in Machado Joseph disease.
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