Serum levels of insulin-like growth factor I and risk of squamous intraepithelial lesions of the cervix.

@article{Wu2003SerumLO,
  title={Serum levels of insulin-like growth factor I and risk of squamous intraepithelial lesions of the cervix.},
  author={Xifeng Wu and Guillermo Tortolero-Luna and Hua Zhao and Deepali G. Phatak and Margaret R. Spitz and Michele Follen},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2003},
  volume={9 9},
  pages={
          3356-61
        }
}
Squamous intraepithelial lesions (SILs) are areas of precancerous growth in the cervix that can be indicative of future cervical cancer. Insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) have been implicated in cancer development. Recent studies have demonstrated that elevated plasma IGF-I levels are associated with increased risk of prostate, lung, colon, and breast cancers. In this case-control study, we analyzed the relationship between serum levels of IGF-I and IGFBP-3… CONTINUE READING

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