Serum levels of ifn-inducible PROTEIN-10 relating to the activity of systemic lupus erythematosus.

@article{Narumi2000SerumLO,
  title={Serum levels of ifn-inducible PROTEIN-10 relating to the activity of systemic lupus erythematosus.},
  author={Shosaku Narumi and Tsutomu Takeuchi and Yoshiro Kobayashi and Kyoko Konishi},
  journal={Cytokine},
  year={2000},
  volume={12 10},
  pages={1561-5}
}
IFN-inducible protein-10 (IP-10) is supposed to act as a specific chemoattractant for Th(1)cells. Since Th(1)cells and IFN-gamma are shown to be important for developing systemic lupus erythematosus (SLE), we examined the relationship between serum IP-10 levels and the disease activity. Serum IP-10 levels were markedly increased in the SLE patients depending on the level of disease activity, whereas not in the patients with rheumatoid arthritis (RA). On the other hand, serum MCP-1 levels were… CONTINUE READING

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