Serum levels of chemokine (C-X-C motif) ligand 9 (CXCL9) are associated with tumor progression and treatment outcome in patients with oral cavity squamous cell carcinoma.

@article{Chang2013SerumLO,
  title={Serum levels of chemokine (C-X-C motif) ligand 9 (CXCL9) are associated with tumor progression and treatment outcome in patients with oral cavity squamous cell carcinoma.},
  author={Kai-Ping Chang and Chih-Ching Wu and K Fang and Chi-Ying Tsai and Yu-Liang Chang and Shiau-Chin Liu and Huang-Kai Kao},
  journal={Oral oncology},
  year={2013},
  volume={49 8},
  pages={802-7}
}
OBJECTIVES The aim of this cohort study was to examine the role of chemokine (C-X-C motif) ligand 9 (CXCL9) on oral cavity squamous cell carcinoma (OSCC). METHODS Sera from 181 OSCC patients, 231 healthy individuals, and 50 OSCC tumor samples were enrolled. CXCL9 expression in tissue samples was analyzed by quantitative real-time PCR and immunohistochemistry. CXCL9 serum concentrations were measured by enzyme-linked immunosorbent assay. Effects of CXCL9 on OSCC cell function were investigated… CONTINUE READING
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