Serum levels of angiopoietin-2 are associated with the growth of multiple myeloma.

@article{Pappa2013SerumLO,
  title={Serum levels of angiopoietin-2 are associated with the growth of multiple myeloma.},
  author={Constantina A. Pappa and George E Tsirakis and Panagiotis Samiotakis and Maria Tsigaridaki and Athanasios Alegakis and Nectaria Goulidaki and Michael G. Alexandrakis},
  journal={Cancer investigation},
  year={2013},
  volume={31 6},
  pages={385-9}
}
Angiopoietins and their receptor, Tie-2, have crucial role in angiogenesis. We measured serum levels of angiopoietin-2 (Ang-2), soluble Tie-2, and factors of burden and prognosis in myeloma (LDH, CRP, beta-2 microglobulin, and interleukin-6) in 55 newly diagnosed patients, with 30 of them in plateau phase, in order to note correlations among them. Levels of Ang-2 were higher in patients in advanced stage of disease, decreased in plateau phase, and correlated with all other factors. Circulating… CONTINUE READING
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