Serum levels of IgG4 and soluble interleukin-2 receptor in patients with coronary artery disease.

@article{Sakamoto2012SerumLO,
  title={Serum levels of IgG4 and soluble interleukin-2 receptor in patients with coronary artery disease.},
  author={Aiko Sakamoto and Nobukazu Ishizaka and Kan Saito and Yasushi Imai and Hiroyuki Morita and Kazuhiko Koike and Takahide Kohro and Ryozo Nagai},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2012},
  volume={413 5-6},
  pages={577-81}
}
BACKGROUND Immunoglobulin G4 (IgG4)-related immuno-inflammation has been suggested to play a role in the development of remodeling of arterial wall. We investigated the association between serum concentrations of IgG4 or soluble interleukin-2 receptor (sIL-2R) and coronary artery disease (CAD). METHODS Serum concentrations of IgG4 and sIL-2R were measured in 286 patients who underwent coronary angiography. RESULTS In patients with CAD, the medians of serum concentrations of IgG4 (39.3 mg/dl… CONTINUE READING