Serum levels of IGF-I and BRCA penetrance: a case control study in breast cancer families

@article{Pasanisi2011SerumLO,
  title={Serum levels of IGF-I and BRCA penetrance: a case control study in breast cancer families},
  author={Patrizia Pasanisi and Eleonora Bruno and Elisabetta Venturelli and Siranoush Manoukian and Monica Barile and Bernard Peissel and Clelia de Giacomi and Bernardo Bonanni and Jacopo Berrino and Franco Berrino},
  journal={Familial Cancer},
  year={2011},
  volume={10},
  pages={521-528}
}
High serum levels of insulin-like growth factor I (IGF-I) are associated with an increased risk of sporadic breast cancer (BC). The aim of the present work is to evaluate the association between IGF-I and hereditary BC risk, using a case–control approach. The work represents an “ad interim” cross-sectional analysis of an ongoing study with a prospective design whose aim is to recruit a cohort of women belonging to high genetic risk families to test potential modulators of penetrance and… CONTINUE READING
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