Serum levels and genotype distribution of α1-antitrypsin in the general population.

@article{Ferrarotti2012SerumLA,
  title={Serum levels and genotype distribution of α1-antitrypsin in the general population.},
  author={Ilaria Ferrarotti and Gian Andri Thun and Michele Zorzetto and Stefania Ottaviani and Medea Imboden and Christian Schindler and Arnold von Eckardstein and Lucia Rohrer and Thierry Rochat and Erich W. Russi and Nicole Probst-Hensch and Maurizio Luisetti},
  journal={Thorax},
  year={2012},
  volume={67 8},
  pages={669-74}
}
RATIONALE α1-Antitrypsin (AAT) deficiency is one of the commonest rare respiratory disorders worldwide. Diagnosis, assessment of risk for developing chronic obstructive pulmonary disease (COPD), and management of replacement therapy require the availability of precise and updated ranges for protein serum levels. OBJECTIVE This paper aims to provide ranges of serum AAT according to the main genotype classes in the general population. METHODS The authors correlated mean AAT serum levels with… CONTINUE READING
31 Citations
30 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 31 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 30 references

SERPINA 1 gene variants in subjects from the general population with reduced alpha 1 - antitrypsin level

  • M Zorzetto, EW Russi, O Senn
  • Clin Chem
  • 2008

Similar Papers

Loading similar papers…