Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity

@inproceedings{Suzuki2012SerumLO,
  title={Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity},
  author={Fumihito Suzuki and T Kubota and Yasunari Miyazaki and Kinya Ishikawa and Masashi Ebisawa and Shunsei Hirohata and Takashi Ogura and Hidehiro Mizusawa and Toshio Imai and Nobuyuki Miyasaka and Toshihiro Nanki},
  booktitle={Arthritis research & therapy},
  year={2012}
}
INTRODUCTION Polymyositis (PM) and dermatomyositis (DM) are chronic inflammatory muscle diseases, in which chemokines are thought to contribute to inflammatory cell migration into muscle. In this study, we retrospectively analyzed the expressions of CX3CL1/fractalkine and its corresponding receptor, CX3CR1, in muscle and lung with interstitial lung disease (ILD) of PM patients and DM patients, and determined the correlation between serum soluble CX3CL1 level and disease activity. METHODS… CONTINUE READING