Serum level and tissue expression of c-erbB-2 protein in lung adenocarcinoma.

@article{Osaki1995SerumLA,
  title={Serum level and tissue expression of c-erbB-2 protein in lung adenocarcinoma.},
  author={Toshihiro Osaki and Tetsuya Mitsudomi and Takahiko Oyama and Ryoichi Nakanishi and Kosei Yasumoto},
  journal={Chest},
  year={1995},
  volume={108 1},
  pages={157-62}
}
Serum levels of c-erbB-2 protein were measured by an enzyme immunoassay in 64 patients with lung adenocarcinoma. Immunohistochemical staining was performed in 40 of these tumors. The mean serum concentration was 16.5 +/- 8.5 U/mL (range: 3.4 to 49.0) in patients with lung adenocarcinoma, whereas it was 14.0 +/- 3.7 U/mL (range: 6.9 to 20.9) in 15 controls (1 U/mL = 0.61 ng/mL). Elevated concentrations (> or = 22.0 U/mL, control mean + 2 SD) were observed in 17/64 lung adenocarcinoma patients… CONTINUE READING
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