Serum leptin monitoring in anorectic patients during refeeding therapy.

  title={Serum leptin monitoring in anorectic patients during refeeding therapy.},
  author={S Lob and James M Pickel and Martin Bidlingmaier and Larry J. Schaaf and Herbert Backmund and Monika Gerlinghoff and Guenter Karl Stalla},
  journal={Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association},
  volume={111 5},
Circulating concentrations of leptin are exceedingly low in severe malnutrition as seen in the acute state of anorexia nervosa (AN). During refeeding therapy plasma leptin levels increase to normal and in some cases peak at values in excess of the BMI of matched controls even before a normal body weight has been achieved. Peak leptin levels are possibly the cause of an increased energy expenditure during this stage of the disorder and might predispose to renewed weight loss (rebound phenomenon… CONTINUE READING


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