Serum leptin in dialysis renal osteodystrophy.

@article{Coen2003SerumLI,
  title={Serum leptin in dialysis renal osteodystrophy.},
  author={Giorgio Coen and Paola Ballanti and Maria Stephanie Fischer and Alessandro Balducci and Santo Calabria and Luisa Colamarco and Giacomo Di Zazzo and Francesca Lifrieri and Micaela Manni and Daniela Sardella and Italo Nofroni and Ermanno Bonucci},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={2003},
  volume={42 5},
  pages={
          1036-42
        }
}
BACKGROUND The hormone leptin is considered to have a role in the prevention of osteoporosis and probably acts on bone tissue through inhibition of osteoclasia. Its action has been attributed to interference in osteoprotegerin (OPG)/OPG-ligand equilibrium. Contradictory data also have been reported, casting doubts on the positive effect on bone mass of the hormone, at least in males. To date, the relation between serum leptin levels of dialysis patients and renal osteodystrophy, defined by… CONTINUE READING

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