Serum leptin in children and young adults with inflammatory bowel disease.

@article{Hoppin1998SerumLI,
  title={Serum leptin in children and young adults with inflammatory bowel disease.},
  author={Alison G Hoppin and Lee M. Kaplan and David Zurakowski and Alan M. Leichtner and Athos Bousvaros},
  journal={Journal of pediatric gastroenterology and nutrition},
  year={1998},
  volume={26 5},
  pages={500-5}
}
BACKGROUND Pediatric inflammatory bowel disease is often associated with growth failure and inadequate energy intake. Although several circulating cytokines are known to be elevated in inflammatory bowel disease, the mechanism for the related anorexia has not been described. Leptin is a newly recognized circulating protein that is an important regulator of appetite and energy metabolism; leptin levels are elevated in several animal models of inflammation. This study was conducted to determine… CONTINUE READING