Serum keratan sulfate is a promising marker of early articular cartilage breakdown.

@article{Wakitani2007SerumKS,
  title={Serum keratan sulfate is a promising marker of early articular cartilage breakdown.},
  author={Shigeyuki Wakitani and Masashi Nawata and Amu Kawaguchi and Takahiro Okabe and Kunio Takaoka and Takahiro Tsuchiya and Ryosuke Nakaoka and Hiroshi Masuda and Kyosuke Miyazaki},
  journal={Rheumatology},
  year={2007},
  volume={46 11},
  pages={1652-6}
}
OBJECTIVES To find serum markers that may serve as indices for an early diagnosis of degeneration or damage of the articular cartilage. METHODS Twenty-four healthy volunteers, 19 individuals with knee trauma (KT) and 31 with knee osteoarthritis (OA) were evaluated. KT patients were divided into a group (n = 5) with an injury <2 months old (recent KT) and a group (n = 14) with that >2 months old (old KT). Articular cartilage damage was assessed using either arthroscopy or direct observation… CONTINUE READING

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