Serum ionized magnesium levels and ionized calcium-to-magnesium ratios in adult patients with sickle cell anemia.

@article{Zehtabchi2004SerumIM,
  title={Serum ionized magnesium levels and ionized calcium-to-magnesium ratios in adult patients with sickle cell anemia.},
  author={Shahriar Zehtabchi and Richard H. Sinert and Stephan Rinnert and Betty Shefts Chang and Christian Heinis and Rachel A. Altura and Bella T. Altura and B. Mauricio Altura},
  journal={American journal of hematology},
  year={2004},
  volume={77 3},
  pages={
          215-22
        }
}
Low levels of total magnesium in sickle cell erythrocytes have been linked to increased sickling due to cell dehydration. We tested the null hypothesis that adult sickle cell anemia (SCA) patients have the same serum level of ionized Mg (Mg(2+)) and Ca(2+)/Mg(2+) ratio as healthy African Americans (AA) and healthy Caucasians (CAUC). We measured serum Mg(2+) and ionized calcium (Ca(2+)) with ion-selective electrodes and calculated the serum Ca(2+)/Mg(2+) ratios in patients with SCA and control… CONTINUE READING
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