Serum interleukin-6 levels correlate with the severity of dementia in Down syndrome and in Alzheimer's disease.

@article{Klmn1997SerumIL,
  title={Serum interleukin-6 levels correlate with the severity of dementia in Down syndrome and in Alzheimer's disease.},
  author={J{\'a}nos K{\'a}lm{\'a}n and A. G{\'e}mesn{\'e} Juh{\'a}sz and Glen Laird and Paul Dickens and Tam{\'a}s J{\'a}rd{\'a}nh{\'a}zy and Agnes Riman{\'o}czy and Imre Boncz and W LI Parry-Jones and Zolt{\'a}n Janka},
  journal={Acta neurologica Scandinavica},
  year={1997},
  volume={96 4},
  pages={236-40}
}
INTRODUCTION Inflammatory processes are suspected in the pathomechanism of Alzheimer's dementia (AD) but the serum and cerebrospinal fluid (CSF) levels of inflammatory cytokines are not yet determined in the different forms of the disorder. SUBJECTS AND METHODS Interleukin-6 (IL-6) levels were examined in the sera and CSF of patients with mild-moderate and severe stage of late onset sporadic type of AD and in the sera of demented Down syndrome (DS) probands with similar stages of AD and… CONTINUE READING

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