Serum interleukin-6 level but not genotype predicts survival after resection in stages II and III gastric carcinoma.

@article{Liao2008SerumIL,
  title={Serum interleukin-6 level but not genotype predicts survival after resection in stages II and III gastric carcinoma.},
  author={Wei-Chih Liao and Jaw-town Lin and Chun-Ying Wu and S F Huang and M Lin and Ariel Sing-Huei Wu and Yu-jie Huang and Ming-Shiang Wu},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2008},
  volume={14 2},
  pages={428-34}
}
PURPOSE It has been suggested that interleukin-6 (IL-6) is a prognostic indicator for survival in patients with gastric carcinoma, but this has not been proved using survival analysis. In Asians, the -634G allele is associated with increased IL-6 production. The objective of this study was to evaluate the association between serum IL-6 levels, -634G/C polymorphism, and overall survival after resection for gastric carcinoma. EXPERIMENTAL DESIGN A total of 155 consecutive patients with gastric… CONTINUE READING