Serum interleukin-18 concentrations are increased in the polycystic ovary syndrome: relationship to insulin resistance and to obesity.

@article{EscobarMorreale2004SerumIC,
  title={Serum interleukin-18 concentrations are increased in the polycystic ovary syndrome: relationship to insulin resistance and to obesity.},
  author={H. Escobar-Morreale and J. Botella-Carretero and G. Villuendas and J. Sancho and J. S. San Mill{\'a}n},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2004},
  volume={89 2},
  pages={
          806-11
        }
}
Low-grade chronic inflammation is involved in the pathogenesis of the metabolic syndrome and atherosclerosis, and serum levels of inflammatory cytokines are useful cardiovascular risk markers. We have studied serum IL-18 concentrations in women with polycystic ovary syndrome (PCOS), focusing on its relationship with obesity and indexes of insulin resistance. Sixty consecutive women with PCOS and 34 healthy women were recruited. Serum levels of IL-18 and lipid and hormone profiles were measured… Expand
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