Serum insulin-like growth factor II in chronic liver disease

Insulin-like growth factor II is secreted primarily by the liver and is reported to be transcribed in many primary hepatocellular carcinoma (PHC) cell lines. We have studied diagnostic significance of serum IGF- II in chronic liver diseases using specific enzyme immunoassay. Serum IGF-II levels (mean±se) were decreased in chronic hepatitis (538 ±51 ng/ml; N… (More)