Serum hepatitis C virus (HCV)-RNA and response to alpha-interferon in anti-HCV positive chronic hepatitis.

@article{Magrin1992SerumHC,
  title={Serum hepatitis C virus (HCV)-RNA and response to alpha-interferon in anti-HCV positive chronic hepatitis.},
  author={Silvio Magrin and Antonio Crax{\`i} and Carmelo Fabiano and Germana Fiorentino and Luciana Marino and Piero Luigi Almasio and Giovan Battista Pinzello and Ugo Palazzo and Massimiliano Vitale and Angela Maggio},
  journal={Journal of medical virology},
  year={1992},
  volume={38 3},
  pages={200-6}
}
Hepatitis C virus (HCV) replication was assessed before and during alpha-interferon (IFN) treatment in 22 anti-HCV positive patients with posttransfusion or sporadic chronic hepatitis (CH). Eleven patients were "responders" and 11 patients "non-responders" to IFN. Thirteen anti-HCV negative healthy subjects and five anti-HCV negative patients with autoimmune CH served as controls. Serum HCV-RNA was detected by the polymerase chain reaction (PCR) in all untreated anti-HCV positive patients but… CONTINUE READING

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