Serum -glutamyl transpeptidase activity in alcoholism.

@article{Rosalki1972SerumT,
  title={Serum -glutamyl transpeptidase activity in alcoholism.},
  author={Sidney B. Rosalki and Dhanvanthi Rama Rau},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={1972},
  volume={39 1},
  pages={
          41-7
        }
}
  • S. Rosalki, D. Rau
  • Published 1 June 1972
  • Medicine
  • Clinica chimica acta; international journal of clinical chemistry
View on PubMed
doi.org
409 Citations
Highly Influential Citations
10
Background Citations
18
Methods Citations
49
Results Citations
1

409 Citations

Serum enzyme levels in alcoholism and drug dependency.
TLDR
Measurement of GGTP is more useful as a screening test for involvement of the liver in alcoholics and drug dependent patients than that of the other enzymes.
Serum gamma-glutamyl transpeptidase and chronic alcoholism
TLDR
It is shown that serum gamma-glutamyl transpeptidase is persistently elevated in patients with clinically obvious liver injury, but only in 22% of chronic alcoholics without significant liver disease.
Plasma gamma-glutamyl transpeptidase in heroin addicts.
Serum gamma-glutamyltransferase activity in alcoholism
SummaryA study of 1234 hospitalized alcoholic patients for abnormal liver function parameters has indicated that serum gamma-glutamyltransferase (GGT) is the parameter most frequently found to be…
Serum gamma glutamyl transpeptidase in liver disorders.
Significance of gamma-glutamyl transferase (GGT) activity measurements in alcohol-induced hepatic injury.
Experimental evidence is presented that the determination of gamma-glutamyl transferase (GGT) activity in serum is useful in the assessment of alcohol-induced liver disease and for demonstrating to…
Alcohol and gamma-glutamyltransferase
SummaryThe determination of gamma-glutamyltransferase (GGT) activity in the serum is commonly used as a screening test for alcoholism, since striking elevations of serum GGT activities can be…
High-sensitivity γ-glutamyltransferase fraction pattern in alcohol addicts and abstainers.
SERUM γ-GLUTAMYL-TRANSPEPTIDASE ISOFORMS IN ALCOHOLIC LIVER DISEASE
TLDR
Electrophoretic separation of multiple forms of gamma GT has high sensitivity and good reproducibility and may be proposed as a complementary test in the diagnosis of alcoholic liver disease.
Diagnostic of alcoholism: how useful is the combination of gamma glutamyl transferase with different biochemical markers?
...
...

References

SHOWING 1-10 OF 17 REFERENCES
Serum glutamic oxalacetic transaminase activity in acute and chronic alcoholism.
TLDR
The ingestion of alcohol in the chronic alcoholic may lead to cellular damage that may become irreversible after a period of time, with subsequent replacement of liver parenchyma with fibrous tissue and the development of Laennec's cirrhosis.
Serum gamma-glutamyl transpeptidase activity in myocardial infarction.
TLDR
The study of serum y-glutamyl transpeptidase activity in hepatobiliary disease has recently aroused much clinical interest and was suggested by the importance of glutamic acid in heart metabolism and by the increase of this amino acid in the serum of patients with myocardial infarction.
Determination of Serum γ-Glutamyl Transpeptidase Activity and its Clinical Applications
TLDR
The L-y-g1utamyl-p-nitroanilide concentration of the substrate and pH chosen were those suggested by Orlowski (1965) and this concentration was found to be optimal, but because of the lower volume of serum in the incubation mixture the final concentration in the reaction mixture is slightly higher (5.6 mmol/I instead of 5·0 mmol/l).
Multiple serum enzyme analyses in chronic alcoholics.
TLDR
In alcoholics the increased serum activity of the intramitochondrial enzyme, glutamate dehydrogenase, suggests a rather severe liver damage in nearly half of the patients.
A soluble form of γ-glutamyl transpeptidase in human tissues
A Micromethod for the Estimation of Serum Bilirubin
TLDR
The failure, up to the present, to obtain good films, appears to rule out the method for this purpose unless the third method mentioned above can be made to bear fruit, but the rapidity of preparation, together with the suggestion of better results on culture, merits further consideration.
Alcoholic fatty liver in man on a high protein and low fat diet.
A simplification of Kind and King's method for determination of serum phosphatase.
  • P. Hansen
  • Medicine
    Scandinavian journal of clinical and laboratory investigation
  • 1966
TLDR
A Simplification of Kind and King's Method for Determination of Serum Phosphatase and its Applications in Clinical and Laboratory Investigation.
Microanalysis in Medical Biochemistry
TLDR
Micro- analysis in medical biochemistry, Micro-analysis in medicalBiochemistry, and Micro- Analysis in Medical biochemistry .
Serum γ-Glutamyl Transpeptidase Activity in Liver Disease
...
...