Serum glomerular binding activity is highly correlated with renal disease in MRL/lpr mice.

@article{Bernstein1993SerumGB,
  title={Serum glomerular binding activity is highly correlated with renal disease in MRL/lpr mice.},
  author={Kara A Bernstein and D Bolshoun and James B Lefkowith},
  journal={Clinical and experimental immunology},
  year={1993},
  volume={93 3},
  pages={418-23}
}
The pathogenesis of lupus nephritis is felt to be mediated by anti-DNA antibodies. However, the anti-DNA response and renal disease do not entirely correspond. We recently developed a new assay which detects immune elements based on their ability to bind glomeruli as an alternative approach to understanding the pathogenesis of this disorder. The glomerular… CONTINUE READING