Serum free light chains for monitoring multiple myeloma.

  title={Serum free light chains for monitoring multiple myeloma.},
  author={Graham Peter Mead and Hugh D Carr-Smith and Mark Trehane Drayson and Gareth J Morgan and J. Anthony Child and Arthur R Bradwell},
  journal={British journal of haematology},
  volume={126 3},
Monoclonal immunoglobulin free light chains (FLC) are found in the serum and urine of patients with a number of B-cell proliferative disorders, including multiple myeloma. Automated immunoassays, which can measure FLC in serum, are useful for the diagnosis and monitoring of light chain (AL) amyloidosis, Bence Jones myeloma and non-secretory myeloma patients. We report the results of a study investigating the utility of serum FLC measurements in myeloma patients producing monoclonal intact… CONTINUE READING


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