Serum erythropoietic activity in the rat around birth.

  title={Serum erythropoietic activity in the rat around birth.},
  author={Med.-Dir. Dr. O. Nagel and Jens Nagel},
  journal={Biology of the neonate},
  volume={46 1},
Using a fetal rat liver cell bioassay, serum erythropoietic activity was tested in non-suckled newborn rats comparatively to 21-day-old rat fetuses at time 0 or after 2 h of surviving. The number of erythroid colonies (CFUe) is significantly greater in cultures with neonatal and fetal rat serum after 2 h of surviving than in cultures with fetal rat serum sampled at time 0. These results suggest a release of erythropoietin or erythropoietin-like substances in response to a short hypoxic phase… CONTINUE READING

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