Serum endocan levels are increased in patients with inflammatory bowel disease.

  title={Serum endocan levels are increased in patients with inflammatory bowel disease.},
  author={T. Voiosu and P. Bălănescu and A. Benguș and A. Voiosu and C. Băicuș and M. Barbu and Anca Lădaru and C. Nițipir and B. Mateescu and M. Diculescu and R. Voiosu},
  journal={Clinical laboratory},
  volume={60 3},
BACKGROUND Endocan is a marker of angiogenesis previously studied in various types of cancer and inflammatory conditions. Its expression is influenced by vascular endothelial growth factor A (VEGF A) and tumor necrosis factor alpha (TNF alpha), cytokines involved in pathogenetic pathways in inflammatory bowel disease (IBD). The aim of this study was to determine whether serum endocan levels were increased in IBD patients. METHODS We conducted an exploratory pilot study. Serum endocan levels… Expand
The role of endocan and selected pro-inflammatory cytokines in systemic lupus erythematosus
A higher serum level of endocan in SLE patients indicates its possible role in the pathogenesis of the disease and reflects endothelial dysfunction. Expand
Clinical significance of endocan in Behçet’s disease patients: A potential marker of disease activity
Serum endocan may serve as a potential marker of disease activity in Behcet disease and patients with genital ulcers, papulopastular lesions and arthritis showed higher serum endOCan levels. Expand
Characteristics of Serum Endocan Levels in Infection
Serum endocan level was not identified as a prognostic factor of bacteremia, and further prospective study concerning the relationship between serum endOCan level and b acteremia would be needed. Expand
Endocan Measurement for Active Behçet Disease.
Serum endocan level may be a new marker in evaluation of both the prognosis and activity of Behçet disease. Expand
Assessment of Endocan Serum Level in Patients with Behçet Disease: Relation to Disease Activity and Carotid Intima Media Thickness.
Endocan can be used to monitor disease activity and endothelial dysfunction in BD and showed significant positive correlations with erythrocyte sedimentation rate, C-reactive protein, BD Current Activity form, and carotid IMT. Expand
Effect of Non‐Surgical Periodontal Treatment on Gingival Crevicular Fluid and Serum Endocan, Vascular Endothelial Growth Factor‐A, and Tumor Necrosis Factor‐Alpha Levels
Endocan and TNF-α levels, both in GCF and serum, increased from health to periodontitis and decreased with non-surgical periodontal treatment, and within the limits of the study, endocan may be considered as a potential inflammatory marker forperiodontal disease. Expand
The Assessment of Serum Endocan Levels in Children With Juvenile Idiopathic Arthritis.
The high level of serum endocan highlighted the endothelial damage in patients with JIA, and there was a weak negative correlation between Childhood Health Assessment Questionnaire scores of patients withJIA and serum endOCan levels. Expand
Endothelial and Cardiac Dysfunction in Inflammatory Bowel Diseases: Does Treatment Modify the Inflammatory Load on Arterial and Cardiac Structure and Function?
It is suggested that IBD treatment may have the potential to ameliorate CV dysfunction resulting in CV benefits and emerging research perspectives regarding how IBDtreatment could improve CV dysfunction are considered. Expand
The diagnostic and prognostic value of serum endocan in patients with cirrhotic cardiomyopathy
Endocan is a promising biomarker of severity of cirrhosis and may help in the diagnosis of cardiac dysfunction in this population of patients with liver cirrhotic cardiomyopathy. Expand
Clinical Utility of Biomarkers in IBD
This overview is structured in chapters reflecting those four typical situations during the disease course of IBD patents to critically evaluate the potential and value of each of the biomarkers in the specific situation. Expand