Serum dihydrotachysterol levels and biological action in normal man.

  title={Serum dihydrotachysterol levels and biological action in normal man.},
  author={A. Taylor and D. Bikle and M. Norman},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={67 1},
  • A. Taylor, D. Bikle, M. Norman
  • Published 1988
  • Medicine
  • The Journal of clinical endocrinology and metabolism
  • Dihydrotachysterol (DHT2) has been a safe and effective treatment for hypocalcemic disorders for many years, but few assays for quantitation of DHT2 have been developed. Thus little is known about its pharmacokinetics. The 2-fold purpose of this study was 1) to develop a practical method for quantitating DHT2 after oral dosing in normal subjects, and 2) to assess changes in serum DHT2 levels and calcium and phosphorus metabolism after DHT2 administration for 8 days. Peak serum DHT2 levels in… CONTINUE READING
    1 Citations
    Differences in the bioavailability of dihydrotachysterol preparations
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