Serum deprivation and protein synthesis inhibition induce two different apoptotic processes in N18 neuroblastoma cells.

Abstract

N18 are murine neuroblastoma cells that underwent cell death upon serum deprivation or inhibition of protein synthesis by means of cycloheximide (CHX). In both cases, an ultrastructural morphology and an internucleosomal pattern of DNA fragmentation typical of apoptosis were found. However, electron microscopy revealed abundant lipid vesicles in the… (More)

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