Serum cytokine elevations in celiac disease: association with disease presentation.

  title={Serum cytokine elevations in celiac disease: association with disease presentation.},
  author={John Sanil Manavalan and Lincoln Hernandez and Jayesh Girish Shah and John Konikkara and Afzal Jamal Naiyer and Anne Roland Lee and Edward J. Ciaccio and Maria Theresa Minaya and Peter H. R. Green and Govind Bhagat},
  journal={Human immunology},
  volume={71 1},
Celiac disease (CD) is an autoimmune disorder that is triggered by an immune response to gluten in genetically predisposed individuals. Although considered a primary gastrointestinal disease, CD is now known to have widespread systemic manifestations. We attempted to define the nature and role of systemic cytokine levels in the pathophysiology of CD. Multiplex cytokine assays were performed on four different groups of adult patients; patients with active CD (ACD), patients on a gluten-free diet… CONTINUE READING


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