Serum corticosterone as a quantitative test of the phlogistic potency of various agents topically applied in the rat.

Abstract

The application into the rat conjunctiva of various phlogistic agents, such as croton oil, mustard oil and formaldehyde, elicits an increase of serum corticosterone linearly related to the log of the applied concentrations, so that from their parallelized regression lines it is possible to calculate the phlogistic potency of each tested agent in reference… (More)

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