Serum copper concentration as an index of lung injury in rats exposed to hemithorax irradiation.

@article{Ward1988SerumCC,
  title={Serum copper concentration as an index of lung injury in rats exposed to hemithorax irradiation.},
  author={William F. Ward and Agostino Molteni and Edward J. Fitzsimons and Joann M. Hinz},
  journal={Radiation research},
  year={1988},
  volume={114 3},
  pages={
          613-20
        }
}
Serum copper concentration was evaluated as an index of lung injury (monitored by lung prostacyclin production) with respect to the effects of time, dose, dose fractionation, and penicillamine dose modification in rats irradiated to the right hemithorax. Both lung PGI2 production and serum Cu concentration increased with increasing 60Co gamma-ray dose in animals sacrificed 2 or 6 months postirradiation, and the highest values for both responses were observed at the latter autopsy time. At 2… Expand
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