Serum concentrations of vascular endothelial growth factor‐D in angiosarcoma patients

  title={Serum concentrations of vascular endothelial growth factor‐D in angiosarcoma patients},
  author={Yasuyuki Amo and Mikio Masuzawa and Yuhko Hamada and Kensei Katsuoka},
  journal={British Journal of Dermatology},

Three cases report of idiopathic angiosarcoma of the head and neck and literature review.

Herein, we reported 3 cases of angiosarcoma (AS) of the head and neck in old patients, and the etiology, pathogenesis, histopathology, immunohistochemistry, diagnosis, differential diagnosis and

Successful treatment of primary cutaneous angiosarcoma of the nose with sequential chemo- and radiotherapy

Apatinib affect VEGF-mediated cell proliferation, migration, invasion via blocking VEGFR2/RAF/MEK/ERK and PI3K/AKT pathways in cholangiocarcinoma cell

Apatinib inhibit VEGF-mediated cell migration and invasion in CCA cell lines via inhibiting the VEGFR2/RAF/MEK/ERK and PI3K/AKT pathways.

Cutaneous angiosarcoma

For patients with early cutaneous angiosarcoma, surgery combined with radiotherapy is the main treatment method, and cytotoxic chemotherapy is usually adopted at present, however, the long-term prognosis remains unsatisfactory.

Angiogenesis concept in odontogenic keratocyst: A comparative study

The angiogenesis may play an important role in the pathogenesis and the unique clinical behavior of OKC, as indicated by the results of this experimental study.

Expression of Vascular Endothelial Growth Factor in Odontogenic Cysts: Is There Any Impression on Clinical Outcome?

It seems that angiogenesis may have great impression on clinical outcome of OKC, as higher expression of Vascular Endothelial Growth factor in OKC than DC is found.

3D printing technology to control BMP-2 and VEGF delivery spatially and temporally to promote large-volume bone regeneration.

The 3D-printed prevascularized structure could be a promising approach to overcome the size limitation of tissue implants and to enhance bone regeneration.

Association between VEGF -634G/C polymorphism and osteonecrosis of the femoral head susceptibility: a meta analysis.

The results indicated that VEGF -634G/C polymorphism might serve as genetic-susceptibility factor for ONFH.

Systemic effects of initial periodontal therapy with or without adjunctive systemic antibiotics

Les sujets atteints de parodontite non traitee peuvent montrer des pics eleves pendant plusieurs marqueurs inflammatoires dans le serum simultanement. Traitement parodontal non chirurgical avec ou

Radiation Therapy in the Treatment of Cutaneous Angiosarcoma of the Head and Neck

The data show that definitive radiotherapy is safe with acceptable efficacy and should be considered for unresectable tumors, or when resection would result in an unacceptable cosmetic defect or significant morbidity.



Vascular endothelial growth factor-D expression is an independent prognostic marker for survival in colorectal carcinoma.

It is concluded that VEGF-D expression, but not that of its receptor VEGFR-3, is an independent prognostic indicator in CRC and may be associated with disease outcome through the promotion of lymphatic involvement/metastases.

Expression of vascular endothelial growth factors A, B, C, and D and their relationships to lymph node status in lung adenocarcinoma.

The hypothesis that two V EGF family members are involved in lymph node metastasis at two distinct steps; VEGF-C facilitates entry of cancer cells into the lymph vasculature, whereas VEGf-A promotes the growth of metastatic tumor through angiogenesis is supported.

Serum levels of vascular endothelial growth factor in a haemangiosarcoma patient with a newly typed p53 gene point mutation

The patient presented with a dense eruption of erythematous papular lesions over the entire face, upper limbs and upper trunk and died 1 week later of an intracranial haemorrhage, probably related to intracerebral disease.

Serum concentrations of vascular endothelial growth factor in angiosarcomas with and without p53 gene mutation.

The present study was designed to clarify the association between p53 inactivation and VEGF secretion in cases of angiosarcoma and suggest that the malignant transformation of endothelial cells may be characterized by V EGF expression in the presence of p53 gene mutation.

VEGF-D promotes the metastatic spread of tumor cells via the lymphatics

It is demonstrated that lymphatics can be established in solid tumors and implicates VEGF family members in determining the route of metastatic spread and could be blocked with an antibody specific for V EGF-D.

Expression of vascular endothelial growth factor in a human hemangiosarcoma cell line (ISO-HAS)

It is demonstrated that tumor cells of the hemangiosarcoma cell line ISO-HAS express mRNA of V EGF and its two receptors, flt-1 and KDR, and secrete VEGF protein, suggesting that the VEGf-VEGF receptor system plays a role in proliferation and growth of hemangioarcomas.