Serum concentrations of cartilage oligomeric matrix protein, fibrinogen and hyaluronan distinguish inflammation and cartilage destruction in experimental arthritis in rats.

Abstract

OBJECTIVES We investigated if changes in serum/plasma fibrinogen (FIB), hyaluronan (HA) and cartilage oligomeric matrix protein (COMP) levels can be used to differentiate between inflammation and cartilage involvement during arthritis. METHODS Collagen-induced arthritis (CIA), oil-induced arthritis (OIA) and for comparison, experimental autoimmune… (More)

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@article{Larsson2002SerumCO, title={Serum concentrations of cartilage oligomeric matrix protein, fibrinogen and hyaluronan distinguish inflammation and cartilage destruction in experimental arthritis in rats.}, author={Erik Larsson and Helena Erlandsson Harris and J\orgen Lorentzen and A. Larsson and Bengt M{\aa}nsson and Lars Klareskog and Tore Saxne}, journal={Rheumatology}, year={2002}, volume={41 9}, pages={996-1000} }