Serum concentration of IL-18 correlates with disease extent in young children with atopic dermatitis.

@article{Hon2004SerumCO,
  title={Serum concentration of IL-18 correlates with disease extent in young children with atopic dermatitis.},
  author={Kam Lun Hon and Ting Fan Leung and Kwok Chiu Ma and Chun Kwok Wong and Helene Wan and C. K. Lam},
  journal={Pediatric dermatology},
  year={2004},
  volume={21 6},
  pages={619-22}
}
Interleukin (IL)-18 is a pleiotropic cytokine that plays an important role in both type 1 (Th1) and type 2 (Th2) helper T lymphocyte-mediated immunity. Previous studies have suggested that IL-18 may be an inflammatory marker for atopic dermatitis (AD). The purpose of our study was to test whether the serum concentration of IL-18 is a useful inflammatory marker for assessing AD severity in young children. Nineteen AD patients with a median age of 2.2 years (interquartile range 0.7-4.6 years… CONTINUE READING

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