Serum clomipramine and metabolite levels in four nursing mother-infant pairs.

@article{Wisner1995SerumCA,
  title={Serum clomipramine and metabolite levels in four nursing mother-infant pairs.},
  author={Katherine L Wisner and JamesM. Perel and John P. Foglia},
  journal={The Journal of clinical psychiatry},
  year={1995},
  volume={56 1},
  pages={
          17-20
        }
}
BACKGROUND Women with postpartum-onset obsessive compulsive disorder may elect treatment with clomipramine. There is minimal information to guide the clinician who must advise breastfeeding women about clomipramine therapy. METHOD Four clomipramine-treated breastfeeding mother-infant pairs were assessed for serum concentrations of clomipramine, N-desmethylclomipramine, and corresponding 8-hydroxymetabolites. RESULTS Although the mothers exhibited a wide range of serum concentrations, the… CONTINUE READING

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