Serum clara cell protein: a sensitive biomarker of increased lung epithelium permeability caused by ambient ozone.

@article{Broeckaert2000SerumCC,
  title={Serum clara cell protein: a sensitive biomarker of increased lung epithelium permeability caused by ambient ozone.},
  author={Fabrice Broeckaert and K Arsalane and Cedric Hermans and Enrico Bergamaschi and Annalisa Brustolin and Antonio Mutti and Alfred Bernard},
  journal={Environmental Health Perspectives},
  year={2000},
  volume={108},
  pages={533 - 537}
}
Ozone in ambient air may cause various effects on human health, including decreased lung function, asthma exacerbation, and even premature mortality. These effects have been evidenced using various clinical indicators that, although sensitive, do not specifically evaluate the O(3)-increased lung epithelium permeability. In the present study, we assessed the acute effects of ambient O(3) on the pulmonary epithelium by a new approach relying on the assay in serum of the lung-specific Clara cell… CONTINUE READING
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