Serum ceruloplasmin protein expression and activity increases in iron-deficient rats and is further enhanced by higher dietary copper intake.

@article{Ranganathan2011SerumCP,
  title={Serum ceruloplasmin protein expression and activity increases in iron-deficient rats and is further enhanced by higher dietary copper intake.},
  author={Perungavur N. Ranganathan and Yan Lu and Lingli Jiang and Changae Kim and James F Collins},
  journal={Blood},
  year={2011},
  volume={118 11},
  pages={3146-53}
}
Increases in serum and liver copper content are noted during iron deficiency in mammals, suggesting that copper-dependent processes participate during iron deprivation. One point of intersection between the 2 metals is the liver-derived, multicopper ferroxidase ceruloplasmin (Cp) that is important for iron release from certain tissues. The current study… CONTINUE READING