Serum cannabidiol, tetrahydrocannabinol (THC), and their native acid derivatives after transdermal application of a low-THC Cannabis sativa extract in beagles.

  title={Serum cannabidiol, tetrahydrocannabinol (THC), and their native acid derivatives after transdermal application of a low-THC Cannabis sativa extract in beagles.},
  author={Mary Beth Hannon and Kelly A Deabold and Bryce N. Talsma and Alexander V. Lyubimov and Asif Iqbal and Alexander D Zakharov and Lauri-Jo Gamble and Joseph J. Wakshlag},
  journal={Journal of veterinary pharmacology and therapeutics},
Cannabinoids hold promise for treating health problems related to inflammation and chronic pain in dogs, in particular cannabidiol (CBD), and its native acid derivative cannabidiolic acid (CBDA). Information regarding systemic delivery of cannabinoids through transdermal routes is sparse. The purpose of this study was to determine pharmacokinetics of transdermal administration of a low-THC Cannabis sativa extract in healthy dogs. Six purpose-bred research beagles were treated with a transdermal… Expand
3 Citations
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  • C. White
  • Medicine
  • Journal of clinical pharmacology
  • 2019
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