Serum biomarker panels for the detection of pancreatic cancer.

  title={Serum biomarker panels for the detection of pancreatic cancer.},
  author={Randall E. Brand and Brian M. Nolen and Herbert J. Zeh and Peter J. Allen and Mohamad Ali Eloubeidi and Michael J. Goldberg and E. T. G. Elton and Juan Pablo Arnoletti and John D. Christein and Selwyn Maurice Vickers and Christopher James Langmead and Douglas P. Landsittel and David C. Whitcomb and William E. Grizzle and Anna E. Lokshin},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  volume={17 4},
PURPOSE Serum-biomarker based screening for pancreatic cancer could greatly improve survival in appropriately targeted high-risk populations. EXPERIMENTAL DESIGN Eighty-three circulating proteins were analyzed in sera of patients diagnosed with pancreatic ductal adenocarcinoma (PDAC, n = 333), benign pancreatic conditions (n = 144), and healthy control individuals (n = 227). Samples from each group were split randomly into training and blinded validation sets prior to analysis. A Metropolis… CONTINUE READING
67 Citations
50 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 67 extracted citations


Publications referenced by this paper.
Showing 1-10 of 50 references

Similar Papers

Loading similar papers…